Abteilungen

Abteilung Neurodegeneration und Neurorestaurationsforschung

• *Tauber E, Miller-Fleming L, Mason RP, Kwan W, Clapp J, Butler NJ, Outeiro TF, Muchowski PJ, Giorgini F (2011):
  Functional gene expression profiling in yeast implicates translational dysfunction in mutant huntingtin toxicity. J BIOL CHEM, 286(1): 410-9.
  
• *Büttner S, Delay C, Franssens V, Bammens T, Ruli D, Zaunschirm S, de Oliveira RM, Outeiro TF, Madeo F, Buée L, Galas MC, Winderickx J (2010):
  Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner. PLOS ONE. 5(10): e13700.
  
• *de Oliveira RM, Pais TF, Outeiro TF (2010):
  Sirtuins: Common Targets in Aging and in Neurodegeneration. CURR DRUG TARGETS, 11(10 ): 1270-80. (Review)
  
• *Gonçalves SA, Matos JE, Outeiro TF (2010):
  Zooming into protein oligomerization in neurodegeneration using BiFC. TRENDS BIOCHEM SCI, 35(11): 643-51. (Review)
  
• *Outeiro TF, Putcha P, Tetzlaff JE, Spoelgen R, Koker M, Carvalho F, Hyman BT, McLean PJ (2008):
  Formation of toxic oligomeric alpha-synuclein species in living cells. PLOS ONE, 3(4): e1867.

Suchworte: Altern, Alzheimer-Krankheit, Ataxien, Bewegungsstörungen, Gentherapie, Klinische Studien, Parkinson-Krankheit, Tiefe Hirnstimulation